ShainLab/Footprints_v.0.1: Footprints v0.1.0

This release provides the first public version of Footprints (v0.1.0), a software toolkit developed in the Shain Laboratory for identifying and analyzing mutational footprints from genomic sequencing data. Footprints runs a c based tool, foots, that uses samtools to count the number of bases in your bam file with a minimum coverage of your choice.

Footprints implements methods to process somatic variant calls, categorize mutation contexts, and generate summary metrics used in studies of mutational processes, clonal evolution, and tissue‑specific mutational signatures. The utilities included support standardized input formats and integrate with complementary analysis pipelines developed in the Shain Lab.

This initial release corresponds to the version of the code used internally for generating mutational footprint analyses in related publications and datasets.

License: MIT License

Please cite the Zenodo DOI associated with this release when using this software in publications.

Changes in v0.1.0:

• Initial public release of the Footprints toolkit
• Functions for processing somatic variant calls and extracting mutational footprints
• Documentation and example usage included in the repository