PANDORA population-level multimodal MRI association maps

This dataset contains population-level association maps reported in the PANDORA preprint.

Included are statistical images (zstat, cope, -log10(p)) from the example analyses, main experiments, supplementary experiment, and power analysis:

• Example analyses: AD polygenic risk and neuroticism (1K/10K supervoxels and full resolution)
• Experiment 1: lifetime trauma (1K/10K supervoxels and full resolution)
• Experiment 2: anxiety vs depression symptom load (1K/10K supervoxels)
• Experiment 3: EPHA3 rs987748 minor variant (1K/10K supervoxels)
• Experiment 4: early- vs late-diagnosis autism polygenic scores (1K/10K supervoxels)
• Supplementary Experiment S1: smoking, coffee and alcohol (1K/10K supervoxels)
• Power analysis: smoking across 98 sub-modalities  (1K/10K supervoxels and full resolution)

Volume ordering

Within each statistical image file, volumes are ordered as follows.

Examples, Experiment 1 (lifetime trauma), Experiment 3 (EPHA3 rs987748), and smoking power analysis

0 = +  

1 = −

Experiment 2 (anxiety and depressive symptom dimensions)

0 = anxiety+ 1 = depression+ 2 = anxiety−

3 = depression− 4 = anxiety−depression (+)  5 = anxiety−depression (−)

6 = anxiety+depression (+) 7 = anxiety+depression (−)

Experiment 4 (early- vs late-diagnosis autism polygenic scores)

0 = early+ 1 = late+ 2 = early−

3 = late− 4 = early+late (+) 5 = early+late (−)

6 = early−late (+) 7 = early−late (−)

Supplementary Experiment S1 (common substance use)

0 = smoking+ 1 = coffee+ 2 = alcohol+

3 = smoking− 4 = coffee− 5 = alcohol−

6 = smoking+coffee+alcohol (+) 7 = smoking+coffee+alcohol(−)

8 = smoking−coffee (+) 9 = smoking−alcohol (+)

10 = coffee−alcohol (+) 11 = coffee−smoking (+)

12 = alcohol−smoking (+) 13 = alcohol−coffee (+)