Published March 7, 2026 | Version 1.0

Summary Statistics and Analysis Code for: Genetic Modulation of LDL-C and Triglyceride Response to Mediterranean-Style Diet

Authors/Creators

  • 1. ROR icon Ilia State University

Description

Description: > This repository contains the analysis code and complete gene-level summary statistics supporting the manuscript "Genetic Modulation of LDL-C and Triglyceride Response to Mediterranean-Style Diet: Whole-Exome Evidence with a Focus on Plasma Lipoprotein Pathways".

Contents:

  • Analysis Code: R scripts used for data processing, exome-wide association analysis, targeted pathway analysis (Plasma Lipoprotein Assembly, Remodeling, and Clearance), and figure generation. (Also mirrored on GitHub: https://github.com/saba966/Nutrigen_LDL_GWAS) . * Summary Statistics: An Excel workbook containing the full results for both the exome-wide and targeted analyses, including Simes p-values, FDR scores, and minor allele counts for ΔLDL-C and ΔTAG .

Note: Raw individual-level genomic data (WES) are restricted due to ethical and privacy regulations and are not included in this public repository.

Files

Lipid_Nutrigen_WES_R_Script.zip

Files (35.7 kB)

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Additional details

Software

Repository URL
https://github.com/saba966/Nutrigen_LDL_GWAS
Programming language
R