Published March 6, 2026 | Version v1
Dataset Embargoed

Raw Nanopore sequencing data of CD-pore-seq V1: TelN PromethION SRICO_PromeR1 13

  • 1. EDMO icon University of Edinburgh

Description

=Raw Nanopore sequencing data of CD-pore-seq V1=

==Author==
Zicheng Yu1, Zihao Chen1, Thomas C. Williams1,2, Craig J. Anderson1,3,4, Andrew P. Jackson1,*, Martin A.M. Reijns1,*, Martin S. Taylor1,*
1 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, UK.
2 Child Life and Health, University of Edinburgh, UK.
3 German Cancer Research Center, Heidelberg, Germany
4 Department of Translational Oncology, German Cancer Research Center, Munich, Germany.

* Correspondence should be addressed to andrew.jackson@ed.ac.uk, martin.reijns@ed.ac.uk and martin.taylor@ed.ac.uk

==Citation==
'Generalised training for DNA modification detection by nanopore sequencing'

==Description==
Nanopore sequencing data of libraries to train machine learning models to predict single DNA-embedded ribonucleotides.
Ligation kit: LSK-114 (all except for ygDNA) or SQK-NBD114.96 (ygDNA)
Flow-cell version: R10.4.1
Sequencing device: MinION or PromethION (./TelN/PromethION only)

==TelN==
* Sequencing the TelN library (high-complexity randomers surrounding single DNA-embedded ribonucleotides) on a MinION flow-cell (./MinION) or two PromethION flow-cells (PromethION), prepared by CD-pore-seq (with the second strand synthesised by the primer containing TelN recognition sequence, cut and covalently linked by TelN digestion).

Files

Embargoed

The files will be made publicly available on May 7, 2026.