Published March 5, 2026
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NEUROPHYSIOLOGICAL BASIS OF MOTOR AND BALANCE IMPAIRMENTS IN THE CHRONIC PHASE OF ISCHEMIC STROKE AND CONTEMPORARY REHABILITATION APPROACHES
Description
Ischemic stroke is one of the leading causes of long-term disability worldwide and is associated with persistent neurological deficits affecting motor performance and postural control (1). Despite advances in acute stroke management, a significant proportion of patients enter the chronic (residual) phase with lasting impairments. Motor weakness, spasticity, impaired coordination, and balance disorders substantially reduce independence and quality of life. Understanding the neurophysiological mechanisms underlying these impairments is essential for optimizing rehabilitation strategies.
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Additional details
References
- 1.Feigin VL, Norrving B, Mensah GA. Global burden of stroke. Circulation Research. 2017;120(3):439–448.
- 2.Langhorne P, Bernhardt J, Kwakkel G. Stroke rehabilitation. The Lancet. 2011;377(9778):1693–1702.
- 3.Dimyan MA, Cohen LG. Neuroplasticity in the context of motor rehabilitation after stroke. Nature Reviews Neurology. 2011;7(2):76–85.
- 4.Ward NS. Restoring brain function after stroke. Nature Reviews Neurology. 2017;13(4):244–255.
- 5.Pollock A, Baer G, Campbell P, et al. Physical rehabilitation approaches after stroke. Cochrane Database of Systematic Reviews. 2014;CD001920
- 6.Mehrholz J, Thomas S, Werner C, et al. Electromechanical-assisted training for walking after stroke. Cochrane Database of Systematic Reviews. 2017;CD006185.