Published March 5, 2026 | Version v1
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Raw Nanopore sequencing data of CD-pore-seq V1: TelN PromethION SRICO_PromeR1 7

  • 1. EDMO icon University of Edinburgh

Description

=Raw Nanopore sequencing data of CD-pore-seq V1=

==Author==
Zicheng Yu1, Zihao Chen1, Thomas C. Williams1,2, Craig J. Anderson1,3,4, Andrew P. Jackson1,*, Martin A.M. Reijns1,*, Martin S. Taylor1,*
1 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, UK.
2 Child Life and Health, University of Edinburgh, UK.
3 German Cancer Research Center, Heidelberg, Germany
4 Department of Translational Oncology, German Cancer Research Center, Munich, Germany.

* Correspondence should be addressed to andrew.jackson@ed.ac.uk, martin.reijns@ed.ac.uk and martin.taylor@ed.ac.uk

==Citation==
'Generalised training for DNA modification detection by nanopore sequencing'

==Description==
Nanopore sequencing data of libraries to train machine learning models to predict single DNA-embedded ribonucleotides.
Ligation kit: LSK-114 (all except for ygDNA) or SQK-NBD114.96 (ygDNA)
Flow-cell version: R10.4.1
Sequencing device: MinION or PromethION (./TelN/PromethION only)

==TelN==
* Sequencing the TelN library (high-complexity randomers surrounding single DNA-embedded ribonucleotides) on a MinION flow-cell (./MinION) or two PromethION flow-cells (PromethION), prepared by CD-pore-seq (with the second strand synthesised by the primer containing TelN recognition sequence, cut and covalently linked by TelN digestion).

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