Published March 2, 2026
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CLINICAL AND LABORATORY COMPARATIVE ANALYSIS OF GASTROINTESTINAL DISORDERS IN CHILDREN WITH BRONCHIAL ASTHMA AND ATOPIC DERMATITIS
Description
The increasing prevalence of allergic diseases in children necessitates an investigation into additional factors influencing the severity and course of asthma and atopic dermatitis. In recent years, increasing attention has been paid to the gastrointestinal tract as a potential source of chronic inflammation and immune dysfunction.
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Additional details
References
- 1.In children with comorbid bronchial asthma and atopic dermatitis, gastrointestinal disorders are detected more often (70.6%) than with isolated bronchial asthma (51.6%) and atopic dermatitis (43.5%).
- 2.Dysbiotic changes in the intestinal microbiota are significantly more common in comorbidity (76.5%), which is accompanied by an increase in the level of total IgE and signs of immune imbalance.
- 3.The severity of gastrointestinal symptoms and laboratory indicators of inflammation can be considered as an additional factor in the aggravation of the clinical course of allergic diseases in children.
- 4.A comprehensive assessment of the gastrointestinal tract and intestinal microbiota has important diagnostic and prognostic value in the management of children with bronchial asthma and atopic dermatitis.