Published March 1, 2026 | Version v1
Conference paper Open

THE ROLE OF NEUROINFLAMMATION IN THE PATHOGENESIS OF ALZHEIMER'S DISEASE

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Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia worldwide. While amyloid-beta (Aβ) plaques and neurofibrillary tangles have long been considered the central pathological hallmarks of AD, increasing evidence highlights neuroinflammation as a critical contributor to disease onset and progression.

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References

  • 1. Heneka MT, et al. Neuroinflammation in Alzheimer's disease. Lancet Neurology. 2. Calsolaro V, Edison P. Neuroinflammation in Alzheimer's disease. Curr Alzheimer Res. 3. Heppner FL, et al. Immune mechanisms in Alzheimer's disease. Nat Rev Neurosci. 4. Ransohoff RM. How neuroinflammation contributes to neurodegeneration. Science.