Hypoxic-Ischemic Colitis at Griffiths' Point in a Term Infant with Hypoxic-Ischemic Encephalopathy and Acute Kidney Injury Requiring Emergency Subtotal Colectomy
Authors/Creators
- 1. Department of Pediatrics and Pediatric Surgery, Postgraduate Institute of Child Health & Research and KT Children Govt University Teaching Hospital, Rajkot, Gujarat, India
- 2. Lincoln University College, 2, Jalan Stadium, SS7/15 SS7. 47301 Petaling Jaya, Selangor, Malaysia
- 3. Formerly Head, Department of Surgery at Tata Memorial Hospital, Mumbai, India
- 4. J. Watumull Global Hospital & Research Centre, Delwara Road, Mount Abu, Rajasthan, India
Description
Abstract
A term male neonate with moderate Hypoxic-Ischaemic Encephalopathy (HIE) developed persistent rectal bleeding and rising inflammatory markers during therapeutic hypothermia. Despite conservative management, he deteriorated with signs of colonic ischaemia. Imaging suggested segmental hypoperfusion centred at Griffiths’ point at the splenic flexure, a recognised colonic watershed zone. Emergency laparotomy revealed extensive non-viable colon requiring subtotal colectomy with end ileostomy. Histopathology confirmed transmural ischaemic necrosis. This case highlights the vulnerability of neonatal colonic watershed regions to systemic hypoperfusion and underscores the need for early recognition of gastrointestinal complications in infants with HIE.
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wjcds.2026.b1902.pdf
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Additional details
Identifiers
Dates
- Submitted
-
2026-01-16
- Accepted
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2026-02-17
- Available
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2026-02-19