Subclinical Hypothyroidism as An Unexpected Etiology of Recurrent Miscarriages

Abstract

Recurrent miscarriages are a rare occurrence in routine medical practice (1-3% of pregnancies) and represent a significant diagnostic challenge.

Subclinical hypothyroidism (SCH) is the most common thyroid disorder during pregnancy (3-5% of pregnant women) and can be responsible for several obstetric complications such as miscarriage, preterm birth, gestational hypertension, preeclampsia, and increased perinatal mortality. SCH remains an exceptional and still controversial cause of recurrent miscarriages.

We report an original observation of isolated SCH as unexpected etiology of four consecutive spontaneous miscarriages at 10, 14, and 16 weeks of amenorrhea in a 28-year-old Tunisian woman.