Platelet-Rich Plasma Therapy in Male Androgenetic Alopecia: A Case Report and Contemporary Review

Platelet-rich plasma (PRP) therapy has emerged as a promising non-surgical modality for treating androgenetic alopecia (AGA), leveraging autologous growth factors to stimulate follicular regeneration. This report presents the case of a 28-year-old male with Norwood-Hamilton Grade III Vertex AGA, demonstrating early crown thinning, mild frontal recession, and signs of progression toward Grade IV.

The patient exhibited diffuse thinning over the vertex and mid-scalp, with lateral zones relatively preserved. A structured PRP protocol involving intradermal injections was administered over three months. The patient demonstrated significant improvement in hair density and shaft thickness, with enhanced scalp coverage.

These findings are consistent with recent literature supporting PRP’s efficacy in early-to-moderate AGA. The case highlights the importance of standardized protocols, appropriate patient selection, and realistic expectations in optimizing outcomes. PRP continues to gain traction as a safe, minimally invasive option for young men seeking hair restoration.