Unlocking The Multifaceted Properties of Poloxamers: A Evolutionized Non - Ionic Surfactant

Poloxamers are a family of non-ionic, triblock copolymer that consists of a hydrophobic core and chain of polypropylene oxide (PPO) between two hydrophilic chains of polyethylene oxide (PEO). Poloxamers have a molecular weight of between 5,000 and 15,000 g/mol along with distinct characteristics like amphiphilicity, thermoreversible gelation and solubilization of hydrophobic compounds. All these properties make poloxamers highly versatile excipients allowing their use in pharmaceutical formulations, cosmetics and even food processing. In addition to this, they have also been researched in terms of their application in drug delivery systems, gene transfer and scaffolds in tissue engineering. This abstract offers a description of the structure, poloxamers applications, properties and uses. It is extensively applied in different industries, such as pharmaceutical, cosmetic, and food processing. This is a review article covering. the applications, properties and future of poloxamers. We discuss their physicochemical properties, such as solubility, viscosity, and surface tension, as well as their biological properties, including biocompatibility, biodegradability, and immunogenicity. Moreover, we also assess their applications in food, pharmaceuticals and cosmetics, their processing and possible applications in biomedical studies.  In conclusion, this review highlights potential future directions for the research and development of poloxamers..