Published February 19, 2026 | Version v1

When Myxoma Meets Bicuspid Aortic Valve: A Rare and Unexpected Cardiac Association

  • 1. Department of Cardiovascular Surgery B, Ibn Sina University Hospital Center, Faculty of Medecine and Pharmacy of Rabat, Mohammed V University, Rabat, Morocco

Description

Atrial myxoma is the most common primary cardiac tumor in adults. It is generally sporadic, although an embryological origin has been suggested, as tumor cells are thought to arise from mesodermal embryonic remnants trapped within the interatrial septum. Bicuspid Aortic Valve (BAV), on the other hand, represents the most common congenital valvular anomaly. The simultaneous association of these two entities is exceptional and rarely reported in the literature. We report the case of an adult patient without any known genetic syndrome in whom this coexistence was identified. This case raises etiological, diagnostic and therapeutic questions and highlights the importance of a comprehensive cardiovascular evaluation when multiple cardiac abnormalities are present.

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