EMT and polarity-associated transcriptional processes active during lineage commitment in the human embryo.

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here changes in EMT and polarity-associated transcriptional processes during lineage commitment in the human embryo. This included changes in vimentin, BBS9, and PRICKLE4.