Published February 11, 2026
| Version v1.0.1
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Integrating transcriptomics and molecular AOPs to identify T3-dependent regulation of neuronal development in the human neural progenitor test
Authors/Creators
- 1. Maastricht University
- 2. RIVM & Erasmus MC
- 3. RIVM
- 4. RIVM & Utrecht University
Description
Differential gene expression analysis of thyroid hormone (T3) effects for Adverse Outcome Pathway (AOP) research. This study compares hypothyroid (no T3 vs control) and hyperthyroid (high T3 vs control) conditions to identify gene regulation patterns relevant to thyroid hormone disruption.
Notes
This research was conducted as part of the VHP4Safety project, which has received funding from the Dutch Research Council (NWO).
Files
marvinm2/thyroid-aop-omics-v1.0.1.zip
Files
(11.8 MB)
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md5:efd7ab1809da85c2a2ecb9a9eb0cb197
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Additional details
Related works
- Is supplemented by
- Dataset: https://www.ebi.ac.uk/biostudies/vhp4safety/studies/S-VHPS20 (URL)
Software
- Repository URL
- https://github.com/marvinm2/thyroid-aop-omics