Published February 11, 2026 | Version v1
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Addendum: Neu5Gc as a Central Molecular Driver of Chronic Autoimmune and Inflammatory Disease

Description

This addendum integrates Neu5Gc biology into a terrain-based and redox-centered framework of chronic autoimmune and inflammatory disease. Neu5Gc is presented as a diet-derived xeno-autoantigen driving persistent immune activation, oxidative stress, and systemic immune dysregulation beyond pathogen-centric models.

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Addendum_Neu5Gc_Acconciagioco_Calvo_2026.pdf

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