BLUE Protocol

During the application of POCUS and lung ultrasonography, the BLUE protocol (Bedside Lung Ultrasound in Emergency) was developed in the 1990s by Daniel Lichtenstein. It represents a highly relevant tool for the rapid and effective differential evaluation of acute respiratory failure [1]. Lung ultrasound is based on the identification of artifacts resulting from the normal interaction between pleural structures and the lung parenchyma, as well as the potential detection of adjacent pathological findings.
Given the frequent occurrence of interstitial syndromes, pneumothorax, atelectasis, and other conditions in emergency and critical care settings, the use of this technology—and its associated protocol—has become widely consolidated [2].