Factual errors in the Cochrane review (Webster et al, 2023) on betahistine in Menière's Disease

This report documents factual errors identified in the Cochrane Review by Webster et al. (2023) on betahistine in Ménière’s disease (Hydropic Ear Disease).

Errors are grouped by error category and original study, with direct references to the relevant pages of the Cochrane review. The focus is exclusively on concrete, verifiable inconsistencies, misclassifications, omissions, and internal contradictions in study characterisation, analysed populations, outcome reporting, statistical interpretation, and trustworthiness assessment.

Only published clinical trials on betahistine were considered. No unpublished data or confidential industry material were available or used.

The purpose of this report is to enable transparent verification of the identified errors and to support accurate interpretation of the Cochrane review by clinicians, researchers, and guideline developers.