Published February 5, 2026
| Version v1.1.0
Software
Open
ParaDigMa: A toolbox for deriving Parkinson's disease Digital Markers from real-life wrist sensor data
Authors/Creators
- 1. Radboud University, Nijmegen, Netherlands; Radboud University Medical Center, Nijmegen, Netherlands
- 2. Radboud University Medical Center, Nijmegen, Netherlands
- 3. Center for Engineering, Modeling and Applied Social Sciences (CECS), Federal University of ABC (UFABC), Brazil
- 4. Netherlands eScience Center
- 5. Imperial College London
- 6. University of Birmingham
- 7. University of Nottingham
- 8. Radboud University, Nijmegen, Netherlands
Description
The Parkinson's disease Digital Markers (ParaDigMa) toolbox is a Python software package designed for processing and analyzing real-life wrist sensor data to extract digital measures of motor and non-motor signs of Parkinson's disease (PD).
The toolbox processes accelerometer, gyroscope and photoplethysmography signals collected during passive monitoring in daily life. It contains three scientifically validated data processing pipelines: (1) arm swing during gait, (2) tremor, and (3) pulse rate analysis. An orchestrator function enables end-to-end processing from raw data loading to aggregated measures, with automatic data preparation including flexible column mapping and sensor orientation adjustment. The toolbox also provides general functionalities for signal processing and feature extraction, such as filtering, peak detection, and spectral analysis.
ParaDigMa is accompanied by comprehensive documentation including tutorials, installation guides, and API reference. The modular architecture enables researchers to easily extend the toolbox with custom algorithms and functionalities while maintaining compatibility with standardized data formats.
Notes
If you use this software, please cite it using the metadata from this file.
Files
biomarkersParkinson/paradigma-v1.1.0.zip
Files
(21.7 MB)
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Additional details
Related works
- Is supplement to
- Software: https://github.com/biomarkersParkinson/paradigma/tree/v1.1.0 (URL)
Software
- Repository URL
- https://github.com/biomarkersParkinson/paradigma