Advances in Cosmetic Science: A Comprehensive Review of Trends, Technologies, and Applications

Cosmetic science has entered a period of accelerated innovation driven by interdisciplinary advances in dermatology, biotechnology, materials engineering, nanoscience, and digital analytics. This review provides a comprehensive and academically structured evaluation of the contemporary trends, breakthrough technologies, and emerging applications shaping modern cosmetic research and development. Key areas of progress include biomimetic and bioactive ingredients, stem cell–derived actives, nanocarrier-enabled delivery systems, skin–microbiome modulation, regenerative and neurocosmetic approaches, and the integration of artificial intelligence into diagnostic, predictive, and formulation processes. Increasing demands for sustainability have further catalyzed the adoption of green chemistry principles, circular design strategies, and life-cycle assessment tools. This review synthesizes current knowledge, critically examines technological opportunities and regulatory challenges, and outlines future research directions to support evidence-based, safe, and sustainable cosmetic innovation