Published February 4, 2026 | Version v1
Dataset Open

Source data for publication on genetically encoded allosteric antibiotic biosensors

Description

This dataset contains the source data for the figures in the following publication: 

Title: Monitoring intracellular antibiotic concentrations in real-time using allosteric biosensors

Authors: Daria Fleckenstein*, Andreas Kaczmarczyk*, Niklas Breitenbach-Netter, Gili Rosenberg, Roman Peter Jakob, Isabel Sorg, Amanzhol Kurmashev, Carlos Flores, Eva Jiménez-Siebert, Elinor Morris, Steffi Klimke, Sarah Tschudin-Sutter, Andreas Hierlemann, Timm Maier, Christoph Dehio, Urs Jenal#, Knut Drescher#

*equal contribution; #corresponding authors

 

Description of the dataset: 

The data is organized by figures in the publication referenced above. For each figure, there is a XLSX-file that contains the non-image data. For figures that are based on image data, there is a ZIP-archive that contains the raw image data.  

Example: For Figure 2 in the main text of the publication, there following data are available:

  • image data: Fig2.zip
  • non-image data: Fig.2_c_d.xlsx (the letters c,d indicate the panel names within the figure)

Example: For Figure 1 in the main text of the publication, no microscopy images were used. Therefore, the following files are available: 

  • non-image data: Fig.1_d-l.xlsx (the letters d-l indicate the panel names within the figure)

 

Files

Fig2.zip

Files (49.1 GB)

Name Size Download all
md5:709146d8bdc4f36ddbc5b8402073aa16
90.0 kB Download
md5:ffd267155c3d90eb92c8904e7fd5f20c
115.6 kB Download
md5:9f6cdd41ff87545ea548e520d11cc361
27.7 kB Download
md5:f0b9cfc58a799921125a7627de5bba13
139.0 kB Download
md5:a253809092da6e944cf4208a024a2fb1
18.9 GB Preview Download
md5:fc8961ac8d616f111c4284f6e32dec11
8.7 GB Preview Download
md5:1da7a122c953cd2d60dcd0a5422725d2
21.4 GB Preview Download
md5:3ca156f08d743646104612ce59a569eb
39.5 kB Download
md5:4aa139b348d397076f78ebbfc75c3e41
78.5 kB Download
md5:30ecc8fc96438b849f1ccf711d3897ec
44.7 kB Download

Additional details

Funding

Swiss National Science Foundation
NCCR AntiResist (phase II) 225154
Swiss National Science Foundation
Causes and consequences of phenotypic subpopulation formation during bacterial biofilm development 213801
Swiss National Science Foundation
Unmasking the spatial code - How global and local c-di-GMP signaling modules regulate bacterial behavior and virulence 208107
European Commission
PHYMOT - Physics of Microbial Motility 955910