Published March 18, 2026 | Version 0.5.4
Software Open

Physiologically based pharmacokinetic/ pharmacodynamic (PBPK/PD) model of empagliflozin

  • 1. Brown University, Providence, Rohde Island
  • 2. Humboldt-University Berlin, Institute for Theoretical Biology, Berlin
  • 3. Humboldt-Universität zu Berlin, Faculty of Life Sciences, Department of Biology, Institute of Theoretical Biology, Systems Medicine of the Liver; University of Stuttgart, Institute of Structural Mechanics and Dynamics in Aerospace Engineering

Description

This repository provides the empagliflozin physiologically based pharmacokinetic/ pharmacodynamic (PBPK/PD) model.

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Funding

Matthias König was supported by the Federal Ministry of Education and Research (BMBF, Germany) within LiSyM by grant number 031L0054 and ATLAS by grant number 031L0304B and by the German Research Foundation (DFG) within the Research Unit Program FOR 5151 QuaLiPerF (Quantifying Liver Perfusion-Function Relationship in Complex Resection - A Systems Medicine Approach) by grant number 436883643 and by grant number 465194077 (Priority Programme SPP 2311, Subproject SimLivA). This work was supported by the BMBF-funded de.NBI Cloud within the German Network for Bioinformatics Infrastructure (de.NBI) (031A537B, 031A533A, 031A538A, 031A533B, 031A535A, 031A537C, 031A534A, 031A532B).

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matthiaskoenig/empagliflozin-model-0.5.4.zip

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