Published February 3, 2026 | Version v1
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MOST COMMON DISEASES ASSOCIATED WITH HYPERPROLACTINEMIA IN WOMEN AND THEIR RISK FACTORS: A SYSTEMATIC REVIEW

Authors/Creators

  • 1. 1. Ob/Gyn Consultant - Obsetric And Gynecology head of department, althaghor hodpital, Jeddah, KSA.
  • 2. 2. Ob/Gyn Consultant, king Abdullah Medical complex, Jeddah second health cluster, Jeddah, KSA.
  • 3. 3. Obstetrics and Gynecology Consultant, Department of Obstetrics and Gynecology, Maternity and Children Hospital, Makkah, KSA.
  • 4. 4. Obstetric and Gynaecology, KFSHRC, KSA.
  • 5. 5. Obstetrics and Gynecology Resident, Maternity and Children Specialized Hospital, Jeddah, KSA.
  • 6. 6. Family medicine Consultant,Ministry of health, Abha, KSA.
  • 7. 7. MBBS, Service Doctor, King fahad general hospital , jeddah, KSA.
  • 8. 8. MBBS, Service Doctor, Al-Rasras medical Center, Khamis Mushait, KSA.
  • 9. 9. MBBS, Post graduate, ISNC, Jeddah, KSA.
  • 10. 10. MBBS, Medical Intern, King Abdulaziz University Hospital, Jeddah, KSA.
  • 11. 11.MBBS, Medical Intern, Batterjee Medical College, Jeddah, KSA.
  • 12. 12. MBBS, Medical intern, ISNC, Jeddah, KSA.
  • 13. 13. MBBS, Medical intern, king abdulaziz university - rabigh, Rabigh, KSA.
  • 14. 14. Technical Spicalist، Riyadh Regional Laboratory، KSA.

Description

Background: Hyperprolactinemia is a common endocrine disorder in women and represents a frequent cause of menstrual irregularities, infertility,and galactorrhea.It may result from physiological,pathological, or pharmacological causes, with varying clinical implications.

Objective: To systematically review the literature on the most common diseases associated with hyperprolactinemia in women and to identify their associated risk factors.

Methods: A systematic search of PubMed/MEDLINE, Scopus, Web of Science, and Google Scholar was conducted for studies published between 2000 and 2025. Observational studies, clinical cohorts, case control studies, and systematic reviews reporting causes or risk factors of hyperprolactinemia in women were included. Data were synthesized narratively.

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