MRSI semiLASER pulse sequence for Bruker ParaVision 5.1
Authors/Creators
-
1.
Universitat Autònoma de Barcelona
-
2.
The University of Texas MD Anderson Cancer Center
Contributors
Project leader:
Researcher:
Supervisor:
-
1.
Universitat Autònoma de Barcelona
Description
Source code for MRSI semiLASER pulse sequence in Bruker ParaVision 5.1, instructions to compile and deploy the method, and test data sets.
The MRSI-semiLASER sequence was implemented in-house on a 7T Bruker Biospec system running ParaVision 5.1, and its performance was compared to the commercially available CSI-PRESS sequence. The results demonstrated that the MRSI-semiLASER sequence achieved improved spatial distribution homogeneity and up to a 1.2-fold increase in SNR compared to CSI-PRESS in murine brain tumors, allowing a 20% reduction in slice thickness without compromising spectral quality. These findings establish the implemented MRSI-semiLASER sequence as a robust tool for high-resolution MRSI acquisition in mouse brain studies, and it is now available for use by interested researchers.
Notes
All protocols for the animal experiments were approved by the Institutional Animal Care and Use Committee of the Universitat Autònoma de Barcelona (Comitè d'Ètica en la Recerca CERec https://www.uab.cat/ca/etica-recerca accessed September 15th, 2025), Spain (registry number CEEAH 3665).
Files
MRSI semiLASER pulse sequence for Bruker ParaVision 5.1 - Record Content.pdf
Files
(3.1 GB)
| Name | Size | |
|---|---|---|
|
md5:4422219281b9fbfb9c78636418fc157c
|
35.5 kB | Download |
|
md5:301250d9bb079c3a0f51b835fe14a7a0
|
50.5 kB | Preview Download |
|
md5:f776efa42f3da88761e6ea4717372f78
|
36.1 kB | Download |
|
md5:a5c3fb3bca66040b15c28d2c98e90ca9
|
64.7 kB | Preview Download |
|
md5:4ca4808d381cbac6f85f0b3a5be7576c
|
6.0 kB | Preview Download |
|
md5:bba1b84633a0c6af0a6232f463aee8a4
|
54.1 kB | Download |
|
md5:b743fe3abdc57c52881cbd44685f187a
|
122.3 kB | Preview Download |
|
md5:3406df8ca54ae4ce2804bcb108818156
|
588.8 MB | Preview Download |
|
md5:e979a7431ad9f58b7b501e18ae6b71ea
|
202.8 MB | Preview Download |
|
md5:5bbb44a197a1bf699d6a3a0d2518e7bb
|
202.8 MB | Preview Download |
|
md5:921b293512b5a5b77c0f7929e645ac48
|
202.7 MB | Preview Download |
|
md5:1f4ff6d0ab0062eefa0e05252574610d
|
1.4 GB | Preview Download |
|
md5:b8e305428243d32a6f1b0d77e40e3dc3
|
494.6 MB | Preview Download |
Additional details
Additional titles
- Subtitle
- Pulse sequence source code and test data sets
Funding
- European Commission
- INSPiRE-MED - INtegrating Magnetic Resonance SPectroscopy and Multimodal Imaging for Research and Education in MEDicine 813120
- Instituto de Salud Carlos III
- Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN) Grant No. CB06/01/0010
- European Commission
- ATTRACT - breAkThrough innovaTion pRogrAmme for a pan-European Detection and Imaging eCosysTem 777222
- Agencia Estatal de Investigación
- Metabolomic Crossroads: Unraveling The Interplay Between Tumor Microenvironment And Metabolic Reprogramming. Impact In Glioma Therapy Response And MR-Based Follow-Up (TIMER-GLIO). MCIN/AEI/10.13039/501100011033. Grant No. ID2023-147750NB-I00
- Agència de Gestió d'Ajuts Universitaris i de Recerca
- XarTEC SALUT 2021 XARDI 00021