Published February 1, 2026 | Version v1

Analysis Toolkit and Dataset - Long-term Impact of Neonatal Hypoxic-Ischemic Injury on Cortical-Hippocampal Neural Dynamics in Mice

  • 1. University of Toronto, Department of Physiology

Description

Introduction

This repository contains:

  (1) Data - Long-Term Effects of Neonatal HI on Neural Dynamics.xlsx that includes all numerical datasets underlying the figures in the manuscript.

  (2)MATLAB scripts used for data processing, analysis, and figure generation.

These materials support the manuscript:

“Long-term Impact of Neonatal Hypoxic-Ischemic Injury on Cortical-Hippocampal Neural Dynamics in Mice.”

Software Requirements

MATLAB R2019b or later

Open Ephys raw data files

MClust / KlustaKwik (for spike sorting)

Scripts and Applications in the Manuscript

The following scripts were used to generate figures in the associated manuscript:

Figure 2A: HI_spike_time_waveform_check.m

Figures 2C, 2D: HI_waveform_analysis.m

Figures 3A (1–2), 4A, 5A, 6A, 7A, 8C: HI_spike_raster.m

Figure 4B: HI_burst_detect.m

Figures 4C, 5C, 8G, 8H: HI_xCorrelogram.m

Figures 4D, 5D: HI_phase_amplitude_coupling.m

Figures 6B, 7B: HI_calc_coherence.m

Figures 6D, 7D: HI_phase_locking.m

All scripts listed above are included in this repository unless otherwise noted.
External dependencies (e.g., MClust / KlustaKwik) should be obtained from their sources.

License

These data and scripts are provided for the purpose of reproducing the results reported in the associated publication.

Materials may be used for non-commercial academic research only.
Redistribution or modification is not permitted without prior written permission from the authors.

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Additional details

Dates

Available
2026-02-01