Published January 26, 2026 | Version 1.0
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Working alliance as predictor of treatment outcomes in digital health interventions: a protocol for a systematic review

Authors/Creators

  • 1. Complementary and Integrative Digital Health, Institute of Primary Care, UZH and USZ, Switzerland
  • 2. Medical Library, Hospital Universitario Ramón y Cajal, Cochrane Madrid, Madrid, Spain
  • 3. Faculty of Medicine, Universidad Francisco de Vitoria (UFV), Madrid, Spain
  • 4. Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Unidad de bioestadística clínica, Hospital Universitario Ramón y Cajal, (CIBERESP), Cochrane Madrid, Madrid, Spain

Description

Objectives of this systematic review

To assess the association of working alliance with changes in health outcomes (mental health, physical health, quality of life) in digital health interventions in any disease. 

To assess if different components of working alliance (bond, task, goal) have an association with changes in health outcomes (mental health, physical health, quality of life).

To explore the role of the intensity of interaction in the digital health intervention (low vs. high interaction) as an effect modifier of the association of working alliance with changes in health outcomes.

 

Website of Complementary and Integrative Digital Health, Institute of Primary Care, University of Zurich and University Hospital Zurich, Switzerland

Files

WASR_ReviewProtocol_20250126signed.pdf

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Additional details

Dates

Created
2026-01-26
Review protocol