Published January 29, 2026 | Version v1
Dataset Open

Single-nucleus RNA-seq of human post-mortem primary motor cortex (M1) nuclei from ALS-FTD patients, NeuN+ (neuronal) and sorted for TDP-43 low vs. high signal

  • 1. Department of Neurology, University Clinic, University of Ulm, Ulm, Germany
  • 2. ROR icon German Center for Neurodegenerative Diseases
  • 3. Medizinische Fakultät, Universität Ulm

Description

This dataset comprises single-nucleus transcriptomic (RNA-seq) data from nuclei purified from the post-mortem human primary motor cortex (M1) from patients with ALS-FTD, after sorting for TDP-43 nuclear signal (NeuN+, TDP-43 low vs. high). 

Detailed methods and study description in the accompanying publication (tba). 

 

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