Published January 23, 2026 | Version v1
Journal article Open

Renal Involvement in COVID-19 Patients

Authors/Creators

  • 1. Department of internal Medicine, Associate Professor. University of Sinnar, Sinnar, Sudan
  • 2. Fedail Hospital, Khartoum, Sudan
  • 3. Department of of Biochemistry, Sinnar University – Faculty of medicine and health sciences, Sudan
  • 4. Department of Biochemistry and Nutrition, Faculty of medicine, University of Gezira, Sudan.
  • 5. University of Sinnar, Sinnar Teaching Hospital, MBB

Description

Background: Acute kidney injury (AKI) is a critical complication of COVID19, associated with high morbidity and mortality. Data from low resource settings remain scarce.
Objective:To determine the frequency, risk factors, treatment modalities, and outcomes of AKI among hospitalized COVID19 patients in Khartoum,Sudan
Methods:A multicenter crosssectional study was conducted from September to December 2021. Data from 170 hospitalized COVID-19 patients were analyzed using SPSS. AKI was defined and staged using KDIGO criteria.
Results:The frequency of AKI was 66.5% (113/170). Among AKI patients, 69% required renal replacement therapy (RRT), with 51.3% receiving continuous RRT and 48.7% intermittent hemodialysis. Significant predictors of AKI included sepsis (p=0.001) and hemodynamic instability (p=0.001). Mortality was significantly higher in AKI patients (57.5% vs. 31.6%, p=0.001). Comorbidities showed a non-significant trend toward AKI.
Conclusion: AKI is highly prevalent among severe COVID19 patients in Sudan and is associated with markedly increased mortality. Early screening, prompt management of sepsis and hemodynamic instability, and preparedness for RRT are essential in improving outcomes

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