Formulation and Evaluation of Anti-Oxidant Herbal Face Cream by using Pomegranate Leaves Extract

The skin is the largest and most adaptable organ of the human body, forming the outer covering of the integumentary system. It serves as the body’s primary defense barrier against physical, chemical, and biological threats, playing a vital role in protecting internal organs and tissues. Made up of several layers of ectodermal cells, the skin functions as an active barrier that controls the movement of water, electrolytes, and other materials, thereby maintaining internal balance and stability. Beyond protection, it performs important physiological roles such as regulating body temperature, sensing environmental stimuli, supporting immune functions, and participating in metabolic activities like the production of vitamin D and shielding vitamin B folate from ultraviolet rays. Although it seems mostly hairless, human skin actually contains hair follicles across most of its surface except in certain smooth, hair-free areas. The skin also has a remarkable ability to heal itself, mainly through the formation of scar tissue after injury. Because of its complex structure and diverse functions, the skin remains a central subject in dermatological and pharmaceutical studies, especially in the creation of therapies and formulations that promote skin repair, health, and protection. The results showed that all formulations were brown in color, had a characteristic odor, exhibited uniform consistency, and remained stable. The average pH was found to be 6.73 ± 0.078.  Viscosity measurements revealed that the formulations displayed both plastic and pseudo plastic flow behavior. The irritation test confirmed that the creams were non-irritant to the skin. Based on the overall findings, formulation F6 demonstrated superior stability and strong antioxidant potential, making it the most effective among the tested formulations. According to previous research, anthocyanin is the key constituent in pomegranate responsible for its anti-aging effects.