The Biosecurity Handbook: A Practical Guide to Biological Security and AI-Biosecurity Convergence

A comprehensive handbook examining biological security and the convergence of artificial intelligence with biosecurity challenges. This resource provides practical guidance for public health professionals, AI safety researchers, policymakers, laboratory personnel, and students interested in biosecurity. The handbook covers classical biosecurity frameworks, operational biosecurity practices, synthetic biology democratization, AI-enabled biological risks, and governance approaches. Topics include laboratory biosafety levels, dual-use research oversight, gain-of-function research, DNA synthesis screening, pathogen surveillance systems, and the intersection of large language models with biological design tools. Written for both public health/biosecurity professionals seeking AI literacy and AI safety researchers requiring biological context.