Published January 1, 2026 | Version V1
Proposal Open

Development and Validation of ICCA-O (Optimized Adjusted Central Adiposity Index): A Composite Cardio-Metabolic Risk Indicator Integrating BMI, WHR, WtHR, ABSI, and BAI

Description

The paper introduces ICCA-O as a geometric mean-based formula: ICCA-O = (BMI × WHR × WtHR × ABSI × BAI)^{1/5} × 1.50 × (0.01 × Age - 0.40) × sex_factor, categorizing risk from low (<0.65) to very high (>0.85). It demonstrates superior performance over individual indices via ROC analysis, correlations, and regression models on a simulated adult cohort. Sections cover methods, validation, comparisons, global applicability, examples, results, and conclusion emphasizing clinical utility. 

Files

RASI3.pdf

Files (655.2 kB)

Name Size Download all
md5:980f98d5332f06ab6ed33f4d1bca7002
655.2 kB Preview Download