Published July 30, 2020 | Version v1
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Phytochemical screening and antibacterial activity of green synthesis of nanoparticles of Punica granatum

Authors/Creators

  • 1. University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan

Contributors

  • 1. Department of Food Sciences and Technology, University of Swabi, KPK, Pakistan
  • 2. Department of Horticulture, University of Swabi, KPK, Pakistan
  • 3. University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • 4. Department of Food Sciences, Faculty of Bioscience, Cholistan, University of Veterinary & Animal Sciences, Bahawalpur, Pakistan
  • 5. Department of Animal Nutrition, Faculty of Animal Production & Technology, Cholistan, University of Veterinary & Animal Sciences, Bahawalpur, Pakistan
  • 6. Faculty of Allied Health Sciences, Superior College, Lahore, Pakistan

Description

The main objective of this work was to explore Punica granatum phytochemicaly and synthesize nanoparticles from its polar extract. The phytochemical screening test of ethanolic and aqueous extract of P. granatum indicated the presence of tannins, flavonoides, emodins, terpenoids, cardiac glycosides, coumarine, and soluble starch. The aqueous extract showed the presence of tannins, flavonoides, terpenoids, emodins, cardiac glycosides, caumarine, carbohydrates and soluble starch. The extracts were subjected to synthesize gold nanoparticles (Au-NPs) Synthesized Au-NPs were characterized by using Uv-visible, Fourier transform (FT-IR) spectroscopy and AFM (atomic force microscope) analysis. The active phytochemical present in extract are responsible for synthesizes gold nanoparticles (Au-NPs). In addition, synthesized Au-NPs and the methanolic extracts of Punica granatum were screened for their in-vitro antioxidant activity. Au-NPs showed excellent antioxidant potentials. It is concluded that Punica granatum extracts is an outstanding bioreducant for the rapid and green synthesis of Au-NPs, which in turn showed various antioxidant activity. published by the International Journal of Biosciences | IJB

 

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URL
https://innspub.net/phytochemical-screening-and-antibacterial-activity-of-green-synthesis-of-nanoparticles-of-punica-granatum/

Dates

Available
2020-07-30
article published

References

  • Chidambara Murthy KN, Jayaprakasha GK, Singh RP. 2002. Studies on antioxidant activity of pomegranate (Punica granatum) peel extract using in vivo models. Journal of Agricultural and Food Chemistry 50(17), 4791-4795.
  • Daniel MC, Astruc D. 2004. Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology. Chemical reviews 104(1), 293-346.
  • Hossain Z, Yasmeen F, Komatsu S. 2020. Nanoparticles: Synthesis, Morphophysiological Effects, and Proteomic Responses of Crop Plants. International Journal of Molecular Sciences 21(9), 3056.
  • Lee MJ, Jang M, Choi J, Chang BS, Kim SH, Kwak YS, Cho IH. 2016. Korean red ginseng and ginsenoside-Rb1/-Rg1 alleviate experimental autoimmune encephalomyelitis by suppressing Th1 and Th17 cells and upregulating regulatory T cells. Molecular neurobiology 53(3), 1977-2002.
  • Murad W, Ahmad A, Ishaq G, Saleem Khan M, Muhammad Khan A, Ullah I, Khan I. 2012. Ethnobotanical studies on plant resources of Hazar Nao forest, district Malakand, Pakistan. Pakistan Journal of Weed Science Research 18(4).
  • Philip D, Kaleena PK, Valivittan K, Kumar CG. 2011. Phytochemical screening and antimicrobial activity of Sansevieria roxburghiana Schult. and Schult. F. Middle-East Journal of Scientific Research 10(4), 512-8.
  • Rafieian-Kopaei M. 2013. Medicinal plants and the human needs. Journal of Herb Med Pharmacology 1(1).
  • Rauf A, Muhammad N, Khan A, Uddin N, Atif M. 2012. Antibacterial and phytotoxic profile of selected Pakistani medicinal plants. World Applied Sciences Journal 20(4), 540-544.
  • Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, Watson JT. 2001. Long-term use of a left ventricular assist device for end-stage heart failure. New England Journal of Medicine 345(20), 1435-1443.
  • Schippmann U, Leaman DJ, Cunningham AB. 2002. Impact of cultivation and gathering of medicinal plants on biodiversity: global trends and issues. Biodiversity and the ecosystem approach in agriculture, forestry and fisheries.
  • Seebacher W, Simic N, Weis R, Saf R, Kunert O. 2003 Complete assignments of 1H and 13CnmR resonances of oleanolic acid, 18α‐oleanolic acid, ursolic acid and their 11‐oxo derivatives. Magnetic Resonance in Chemistry 41(8), 636-638.
  • Seniya C, Trivedia SS, Verma SK. 2011. Antibacterial efficacy and phytochemical analysis of organic solvent extracts of Calotropis gigantea. Journal of Chemical and Pharmaceutical Research 3(6), 330-336.
  • Shahrajabian MH, Sun W, Cheng Q. 2019. Traditional Chinese medicine and agriculture; organic life and sustainability for future. GSC Biological and Pharmaceutical Sciences 7(1), 091-095.
  • Sultana ARSHIYA, Rahman KHALEEQUR. 2013. Portulaca oleracea Linn. A global Panacea with ethno-medicinal and pharmacological potential. International Journal of Pharmacy and Pharmaceutical Sciences 5, 33-39.
  • Uddin G, Rauf A, Rehman TU, Qaisar M. 2011. Phytochemical screening of Pistacia chinensis var. integerrima. Middle-East Journal of Scientific Research 7(5), 707-711.