Published December 23, 2025 | Version v1
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Clinical profile and evolution of acute poisoning cases in a public hospital in Ica, Peru

Authors/Creators

  • 1. National University San Luis Gonzaga, Ica, Peru

Description

Cases of acute poisoning represent a serious public health problem in developing countries, where 90% of poisoning-related deaths occur. In Peru, epidemiological information on these cases in public hospitals is limited. Strengthening drug surveillance and implementing poison control centres are key to improving case detection and reporting in hospital emergencies. This study aimed to describe the epidemiological characteristics of acute poisoning cases treated in the emergency department of a referral hospital in Ica, Peru, between January 2022 and June 2024 (Table 3). An observational, descriptive, and retrospective study was conducted by analysing variables from admission records and patient medical records. A total of 207 cases were analysed, with a predominance of women (53.1%) and young adults (45.4%), with an average age of 24.3 years. The six-monthly incidence was 26 cases per 10,000 hospital admissions. Most patients were single (66.7%) and had a secondary education (68.1%). The most frequent cases of poisoning were due to psychotropic drugs (25.6%) and pesticides (23.2%), with intentional causes at 62.8%, particularly suicide attempts. Most cases had a mild to moderate course, with hospital stays of 12 to 24 hours. No deaths were recorded. It is concluded that cases of poisoning primarily affect young women, with a significant association between aetiology and case severity.

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Additional details

Cites
Publication: 10.4103/jfmpc.jfmpc_592_23 (DOI)
Publication: 10.1016/j.jsps.2022.06.025 (DOI)
Publication: 10.3390/healthcare11101398 (DOI)
Publication: 10.4103/picr.PICR_181_18 (DOI)
Publication: 10.4103/ijcm.ijcm_92_23 (DOI)
Publication: 10.1016/j.jflm.2019.05.019 (DOI)
Publication: 10.3389/fpubh.2023.1235304 (DOI)
Publication: 10.1590/0102-311x00291620 (DOI)
Publication: 10.1186/s40360-023-00650-5 (DOI)
Publication: 10.2147/OAEM.S414743 (DOI)
Publication: 10.3389/fpubh.2023.1160182 (DOI)
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Figure: 10.3897/pharmacia.72.e155405.figure1 (DOI)
Figure: 10.3897/pharmacia.72.e155405.figure2 (DOI)
Figure: 10.3897/pharmacia.72.e155405.figure3 (DOI)
Figure: 10.3897/pharmacia.72.e155405.figure4 (DOI)
Figure: 10.3897/pharmacia.72.e155405.figure5 (DOI)
Figure: 10.3897/pharmacia.72.e155405.figure6 (DOI)
Figure: 10.3897/pharmacia.72.e155405.figure7 (DOI)
Figure: 10.3897/pharmacia.72.e155405.figure8 (DOI)
Figure: 10.3897/pharmacia.72.e155405.figure9 (DOI)
Figure: 10.3897/pharmacia.72.e155405.figure10 (DOI)

References

  • Aggarwal N, Sawlani KK, Chaudhary SC, Usman K, Dandu H, Atam V, Rani S, Chaudhary R (2023) Study of pattern and outcome of acute poisoning cases at tertiary care hospital in North India. Journal of Family Medicine and Primary Care 12(9): 2047–2052. [Epub 2023 Sep 30. PMID: 38024899; PMCID: PMC10657109] https://doi.org/10.4103/jfmpc.jfmpc_592_23
  • Al-Daghastani T, Naser AY (2022) Hospital admission profile related to poisoning by, adverse effect of and underdosing of psychotropic drugs in England and Wales: An ecological study. Saudi Pharmaceutical Journal: SPJ: The Official Publication of the Saudi Pharmaceutical Society 30(9): 1262–1272. https://doi.org/10.1016/j.jsps.2022.06.025
  • Álvarez E, Pulido B, Rodríguez M (2022) Hospital management of intoxicated patients in emergency departments in Latin America. Revista de Salud Pública 24(3): 345–357.
  • Beigh S, Mahzari A, Alharbi RA, Al-Ghamdi RA, Alyahyawi HE, Al-Zahrani HA, Al-Jadani S (2023) A retrospective study of epidemiological correlations of food, drug and chemical poisoning in Al-Baha, western Saudi Arabia. Healthcare (Basel) 11(10): 1398. [2023 May 11; PMID: 37239684; PMCID: PMC10218255] https://doi.org/10.3390/healthcare11101398
  • Castilla U (2022) Evaluation of the results of the epidemiological surveillance program in public health of the risk of exposure and poisoning by pesticides in the Ica Region [Universidad Nacional San Luis Gonzaga]. https://repositorio.unica.edu.pe/items/43e3880f-6be1-4444-80f1-47abaeed609c
  • Chatterjee S, Verma VK, Hazra A, Pal J (2020) An observational study on acute poisoning in a tertiary care hospital in West Bengal, India. Perspectives in Clinical Research 11(2): 75–80. [Epub 2020 May 6. PMID: 32670832; PMCID: PMC7342341] https://doi.org/10.4103/picr.PICR_181_18
  • Chavez J (2016a) Epidemiological characterization of acute poisonings in Ica hospitals. https://hdl.handle.net/20.500.13028/6067
  • Chavez J (2016b) Epidemiological characterization of acute poisonings treated in MINSA emergency services in the Province of Ica (2012–2016) [Universidad Nacional San Luis Gonzaga]. https://hdl.handle.net/20.500.13028/6067
  • Chávez JH, Castillo PC (2022) Acute pesticide poisoning in the Ica Region. https://hdl.handle.net/20.500.13028/6067
  • Choudhary S, Verma R (2021) Epidemiological profile of intentional poisoning in rural India: A hospital-based study. Journal of Family Medicine and Primary Care 10(2): 722–728.
  • Díaz J (2022) Acute poisoning in patients treated at the Regional Teaching Hospital of Cajamarca, 2012–2018 [Universidad Nacional Mayor de San Marcos]. https://cybertesis.unmsm.edu.pe/handle/20.500.12672/17816
  • García M, López R, Paredes J (2020) Urban patterns in cases of intoxication: Comparative study of exposure to toxicological risk. Journal of Urban Health 96(3): 410–418.
  • García R, Salgado M, Repetto M (2018) Acute poisoning in urban Spain. Revista Española de Salud Pública 92.
  • George AV, Sharma A, Rodha MS, Choudhary B, Bohra GK, Rohila AK, Goel AD (2023) Clinico-epidemiological profile and short-term outcomes of patients with acute poisoning presenting to an emergency of a tertiary care center in western Rajasthan. Indian Journal of Community Medicine 48(5): 734–740. [Epub 2023 Sep 7; PMID: 37970173; PMCID: PMC10637612] https://doi.org/10.4103/ijcm.ijcm_92_23
  • George S, Varghese A, Rajeev A (2019) Patterns and outcomes of acute poisoning. Journal of Family Medicine and Primary Care 8(5): 1509–1513.
  • Huamán J (2019) Organophosphorus poisoning cases in Cusco. https://repositorio.uandina.edu.pe/handle/20.500.12557/3243
  • Huaylla C (2019) Acute poisoning in children in Cajamarca. https://repositorio.unc.edu.pe/handle/20.500.14074/2636
  • Karapirli G, Kandemir E, Akgül Ö, Aksu H, Gündoğmuş Ü (2019) Characteristics of deliberate self-poisoning in Turkey: Gender and psychosocial aspects. Journal of Forensic and Legal Medicine 65: 79–84. https://doi.org/10.1016/j.jflm.2019.05.019
  • Liu S, Ling L, Ma J, Yuan H, Guo Z, Feng Q, Xia X (2023) Trends and profiles of acute poisoning cases: a retrospective analysis. Frontiers in Public Health 11: 1235304. [2023 Sep 5; PMID: 37732094; PMCID: PMC10507702] https://doi.org/10.3389/fpubh.2023.1235304
  • Mathew R, Balan B, Varghese R (2021) Epidemiology and pattern of acute poisoning in rural India. International Journal of Research in Medical Sciences 9(2): 468–472.
  • Ministry of Health (2016) Public health surveillance protocol: Poisoning by chemical substances. https://www.saludcapital.gov.co/CTDLab/Publicaciones/2018/Protocolo_Intoxicaciones_Sustancias_Quimicas.pdf
  • Muñoz M (2021) Poisoning in children and adolescents. Pan American Journal of Public Health 45.
  • Oliveira M, Santos H, Boing A (2020) Acute pesticide poisoning in Brazil. Cadernos de Saúde Pública 36(12). https://doi.org/10.1590/0102-311x00291620
  • Pan American Health Organization (2012) Health in the Americas 2012: Environment and human security.
  • Puma A (2018) Suicide attempts in adolescents in Arequipa. https://repositorio.unsa.edu.pe/items/33f3cb62-a962-49ad-8f87-65eaa9d090c7
  • Rageh OE, Sabra HK, Alammar AA, Alanazi ON, Nagy A, Kabbash IA (2023) Profile and outcomes of acute poisoning in the toxicology treatment and control center at Tanta University Hospital, Egypt. BMC Pharmacology and Toxicology 24(1): 6. [2023 Feb 3; PMID: 36737823; PMCID: PMC9896829] https://doi.org/10.1186/s40360-023-00650-5
  • Reda GB, Abate HK, Mekonnen HM, Gared AZ, Beko ZW (2023) Outcome of poisoning and associated factors among patients admitted at referral hospitals in northwest Ethiopia, 2022: A multicenter retrospective study. Open Access Emergency Medicine 15: 415–425. [2023 Nov 8; PMID: 38022741; PMCID: PMC10640818] https://doi.org/10.2147/OAEM.S414743
  • Waktola LG, Melese EB, Mesfin N, Altaye KD, Legese GL (2023) Prevalence of unfavorable outcome in acute poisoning and associated factors at the University of Gondar comprehensive specialized hospital, Gondar, Northwest Ethiopia: a hospital-based cross-sectional study. Frontiers in Public Health 11: 1160182. [2023 Jun 8; PMID: 37361165; PMCID: PMC10285079] https://doi.org/10.3389/fpubh.2023.1160182
  • World Health Organization (2022) Chemical safety and child health: Prevention and treatment of poisoning. https://www.who.int/publications/i/item/9789240037371
  • Yñigo A (2023) Causal agents of acute poisoning in children under 18 in Apurímac 2019 [Universidad Nacional de San Antonio Abad del Cusco]. https://repositorio.unsaac.edu.pe/handle/20.500.12918/7528