Comparative Analysis of The Relationship between Periodontitis and Cardiovascular Diseases: A Review

Abstract

Periodontitis and cardiovascular diseases are prevalent conditions in today's society. The review underscores both the similarities and disparities in prevalence rates, risk factors, and underlying mechanisms, offering insight into the intricate interplay between these two conditions. This study also aims to investigate the possible associations between periodontitis and cardiovascular diseases. Research has demonstrated that, even in the absence of known cardiovascular risk factors, periodontal disease is linked to CRP. In response to inflammatory cytokines, the liver is the primary site of production for 12- 14 CRP, an acute-phase reactant. Cross-sectional evidence from over a dozen prospective epidemiologic studies showed that CRP was predictive of subsequent vascular events, such as stroke, myocardial infarction, peripheral artery disease, and sudden cardiac death. The relationship between periodontal disease and levels of CRP and IL-6 in racial/ethnic minority groups—especially in the different population—has not received much attention in the literature, despite the abundance of research on the relationship between periodontal disease status and CVD biomarkers." It may be possible to assess periodontal tissue degeneration and forecast the risk of cardiovascular disease in these patients by using several clinical indicators such as CRP level and IL-6.