Published December 19, 2025 | Version v1
Dataset Open

COMPARATIVE STUDY OF THE EFFECT OF EPIDURAL FENTANYL VERSUS MAGNESIUM SULFATE AS ADJUVANTS TO 0.75% ROPIVACAINE IN LOWER LIMB SURGERIES

  • 1. 1. Senior Resident.
  • 2. 2. Assistant professor.
  • 3. 3. Senior Resident.

Description

Background:Epidural anesthesia is frequently chosen for lower limb operations, and adding adjuvants can refine block characteristics while reducing local anesthetic requirements. This randomized, double-blind study evaluated fentanyl and magnesium sulfate as adjuncts to ropivacaine.

Methods:Fifty ASA I II adults were randomly allocated to receive either ropivacaine with fentanyl or ropivacaine with magnesium sulfate. Sensory and motor block onset, regression pattern, analgesic duration, hemodynamic variations, and adverse effects were recorded.

Results:Magnesium sulfate produced a noticeably faster rise in sensory and motor blockade. Fentanyl provided a longer-lasting block with extended analgesia and delayed need for rescue dosing. Hemodynamic trends and side effect incidence remained comparable.

Conclusion: Magnesium sulfate is preferable when rapid block establishment is essential. Fentanyl is advantageous when prolonged postoperative pain relief is the objective. Both agents can be safely used as epidural adjuvants.

 

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