Published December 12, 2025 | Version v1
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What is the most effective treatment for cluster headaches?

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  • 1. Tripdatabase

Description

Oxygen therapy remains a first-line treatment for acute cluster headaches, whereas verapamil and monoclonal antibodies like galcanezumab are effective for prevention, with newer modalities such as vagus nerve stimulation showing potential. Refractory cases may benefit from invasive treatments like DBS and ONS.

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