Published December 11, 2025 | Version v3

SIGnature Datasets (Tutorial)

Authors/Creators

  • 1. Genentech

Description

This dataset is designed for use with the SIGnature package, which enables rapid querying of gene sets across many scRNA-seq datasets by leveraging precomputed gene attribution scores. 

The SIGnature tutorials utilize two cell type attribution folders and one h5ad file:

1. celltype_attributions_lung.tar.gz: this file can be extracted by running "tar -xzf celltype_attributions_lung.tar.gz". This will produce a folder titled "celltype_attributions_lung" that contains data for 2 cell types:

  • pulmonary ionocyte
  • type I pneumocyte

2. celltype_attributions.tar.gz: this file can be extracted by running "tar -xzf celltype_attributions.tar.gz". This will produce a folder titled "celltype_attributions" that contains data for 5 cell types:

  • alveolar macrophage
  • classical monocyte
  • intermediate monocyte
  • macrophage
  • non-classical monocyte

3. tutorial_dataset.h5ad: small h5ad of simulated data to use during signature tutorials

The SIGnature tutorial can then be run by pointing the code to your extracted data.

Files

Files (25.9 GB)

Name Size
md5:14a7121836f7b6eebc486d559395f454
25.2 GB Download
md5:adc99f52afeaa12212d563180511edb4
575.6 MB Download
md5:ef3af3f6423e65db135ba1f1c0e9f0bd
68.6 MB Download