In pediatric patients with invasive fungal infections (such as candidiasis or aspergillosis), how effective and safe are echinocandins (e.g., micafungin, caspofungin), and what is known about optimal pediatric dosing?

Echinocandins are effective and appear to have a favorable safety profile for treating pediatric fungal infections, with some advantages over amphotericin B. Further research is necessary to refine pediatric dosing recommendations.