Published December 9, 2025 | Version v1

Vitamin D: a comprehensive review

  • 1. Serbian Medical Society, Academy of Medical Sciences of the Serbian Medical Society, Belgrade, Serbia
  • 2. Institute for Oncology and Radiology of Serbia, Belgrade, Serbia
  • 3. University Children's Hospital, Belgrade, Serbia
  • 4. University of Belgrade, Faculty of Medicine, Belgrade, Serbia
  • 5. Singidunum University, Faculty of Health, Legal and Business Studies, Valjevo, Serbia
  • 6. Kragujevac Clinical Center, Pediatric Clinic, Kragujevac, Serbia
  • 7. University of Kragujevac, Faculty of Medical Sciences, Kragujevac, Serbia

Description

SUMMARY. Vitamin D (calciferol), i.e. its active metabolite calcitriol [1,25(OH)2D], apart from essential participation
in calcium and phosphorus homeostasis, is an important factor in the regulation of cell proliferation,
differentiation and apoptosis, angiogenesis, immune and hormonal activity and other processes in the
human body. Hence, its optimal balance is extremely important for adequate prenatal and postnatal
growth and development, as well as for the preservation of health in other phases of life. This article
provides a brief overview of the natural sources of vitamin D, its metabolism and physiological role, as
well as current recommendations related to the coverage of its optimal needs.

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Additional details

Dates

Accepted
2025-01-02
Issued
2025-01-10

Software

Repository URL
https://zenodo.org/uploads/17867947
Development Status
Active