Published December 8, 2025 | Version v1

IMPACT OF ORAL CONTRACEPTIVES ON LIPID PROFILE: AN INTEGRATIVE REVIEW

  • 1. ROR icon Universidade Santa Cecília

Description

Oral contraceptives mainly consist of two hormonal classes: estrogen and 
progesterone. Considering that these hormones influence the metabolism of 
carbohydrates and lipids in the female body, the present study aimed to evaluate different 
types of oral contraceptive pills concerning the phases (monophasic, biphasic, and 
triphasic) and especially the type of progestin used in the formula on the female lipid 
profile. The results showed that the effects of this contraceptive method specifically 
depend on the type of progesterone used in the pills, where it was observed that some 
progestins, such as levonorgestrel, are associated with increases in levels of LDL 
cholesterol, triglycerides, and total cholesterol.

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