Age-Wise Analysis of Breast Cancer Incidence and Mortality in India, Asia, and Worldwide: Insights from GLOBOCAN 2022

Background: Breast cancer is the second most common cancer among women worldwide and exhibits significant age- and region-specific variations in incidence and mortality. Understanding these patterns is critical for early detection, preventive strategies, and effective healthcare planning.

 Methods:This review analyzed age-specific breast cancer incidence, mortality, and epidemiological indicators—including Age-Standardized Incidence Rate (ASIR), Age-Standardized Mortality Rate (ASMR), cumulative frequency, and crude rate—among women in India, Asia, and globally using the GLOBOCAN 2022 database. Additionally, relevant research studies were reviewed to summarize risk factors, diagnostic methods, treatment approaches, and preventive strategies.

Results: In 2022, breast cancer accounted for 2.29 million new cases and 666,103 deaths globally. The highest incidence occurred in women aged 50–59, while ASIR peaked in the 80–85+ age group. France reported the highest ASIR (105.4), and Fiji had the highest mortality (182 per 100,000). China, the United States, and India contributed the largest case numbers, with India leading in mortality (51.2%). In India, most cases occurred between ages 50–69, highlighting strong age-dependent trends.

Conclusion: Breast cancer incidence and mortality vary significantly by age and region. These findings underscore the importance of early awareness, age-targeted screening, and preventive interventions to reduce the disease burden, particularly in high-risk populations.