Published December 4, 2025 | Version v1

UPDATES IN PHARMACOTHERAPY FOR CONGESTIVE HEART FAILURE: A REVIEW OF CLINICAL GUIDELINES

  • 1. ROR icon Universidade Santa Cecília

Description

Heart failure (HF) is a clinical syndrome characterized by the heart's 
inability to pump blood adequately. It is a leading cause of morbidity and mortality, 
with increasing prevalence among the elderly. This study analyzes updates to 
clinical guidelines for the management of HF, with an emphasis on 
pharmacological recommendations. The methodology used was the Brazilian 
guidelines from 1993 to 2022, and the latest American guideline was used for 
comparison. According to the 2021 Brazilian Guideline, ACE inhibitors, digitalis, 
aldosterone antagonists, beta-blockers, angiotensin II antagonists, calcium 
antagonists, antiarrhythmics, anticoagulants, diuretics, hydralazine, and 
ivabradine are indicated for the treatment of HF.  

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