FORMULATION AND EVALUATION OF DICLOFENAC SODIUM GEL USING NATURAL POLYMER XANTHAN GUM

This research focused on developing a Diclofenac Sodium topical gel using Xanthan Gum as the gelling polymer. Multiple formulations were prepared by varying polymer concentration, and one optimized batch was selected based on overall performance. The prepared gel showed good physical properties, uniformity, and consistent release behavior. Stability testing confirmed that the optimized formulation remained intact and usable during the study period. When compared with a marketed product, the developed gel showed acceptable and comparable characteristics. Overall, the study successfully produced a stable, effective Diclofenac Sodium gel suitable for further development and practical use.