FORMULATION AND EVALUATION OF EMPAGLIFLOZIN-LOADED ETHOSOMES

The goal of personalised care plans for people with type 2 diabetes is to enhance their quality of life. The major objective of this study was to create a new vesicular drug delivery system (ethosomal gel) that incorporates empagliflozin for the treatment of diabetes. The gel evaluated vesicle size, PDI, Zeta Potential, % Entrapment efficiency, and vesicular shape.According to SEM examination, optimised ethosomal gel was found to have unilamellar vesicles with a size range of a few microns to a few nanometres. DSC and FT-IR studies revealed that empagliflozin was successfully integrated into ethosomes, indicating that it was in an amorphous state within ethosomes.