Nanomedicine: Enhancing Drug Delivery for Effective Pain Management
Authors/Creators
- 1. Bachelor of Dental Surgery (BDS), Department of Dentistry, K.D. Dental College and Hospital, Mathura, India
- 2. Master of Pharmacy (M.Pharm), Department of Pharmacy, Rajiv Academy for Pharmacy, Mathura, India
Description
Background: The disruptive potential of nanomedicine in pain management is through the use of nanocarriers
(liposomes, micelles, polymeric nanoparticles, and emulsions) to improve the improvement in delivery of the
drugs that comprise the pain-relieving chemicals. These systems enhance the solubility and stability of drugs
they target, and have controlled release, which overcomes the drawbacks of the traditional pain therapies.
Methods: This review discusses some nanocarriers used to treat pain specifically; it focuses on their capacity to
traverse physiological boundaries such as the blood-brain barrier (BBB). It also discusses how the size and the
surface functionalization of nanoparticles affect the distribution of drugs and their therapeutic efficacies.
Results: In comparison to the circumstances of the previous administration, nanocarriers have shown increased
bioavailability and decreased toxicity as well as delivery of analgesics, especially in neurological and dental
pain. They are used in periodontal treatment where drugs are released locally, antibacterial compositions and as
supporting implants.
Conclusion: Nanomedicine also works by helping to control the pain by delivering drugs to the body with
precision and in a sustained manner. Nevertheless, there is a need to investigate other areas of safety in the long
run, biodegradability as well as regulatory issues. Additional integration with AI may allow one to be able to
treat pain with personalized and efficient approaches.
Abstract (English)
Background: The disruptive potential of nanomedicine in pain management is through the use of nanocarriers
(liposomes, micelles, polymeric nanoparticles, and emulsions) to improve the improvement in delivery of the
drugs that comprise the pain-relieving chemicals. These systems enhance the solubility and stability of drugs
they target, and have controlled release, which overcomes the drawbacks of the traditional pain therapies.
Methods: This review discusses some nanocarriers used to treat pain specifically; it focuses on their capacity to
traverse physiological boundaries such as the blood-brain barrier (BBB). It also discusses how the size and the
surface functionalization of nanoparticles affect the distribution of drugs and their therapeutic efficacies.
Results: In comparison to the circumstances of the previous administration, nanocarriers have shown increased
bioavailability and decreased toxicity as well as delivery of analgesics, especially in neurological and dental
pain. They are used in periodontal treatment where drugs are released locally, antibacterial compositions and as
supporting implants.
Conclusion: Nanomedicine also works by helping to control the pain by delivering drugs to the body with
precision and in a sustained manner. Nevertheless, there is a need to investigate other areas of safety in the long
run, biodegradability as well as regulatory issues. Additional integration with AI may allow one to be able to
treat pain with personalized and efficient approaches.
Files
IJCPR,Vol17,Issue11,Article149.pdf
Files
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Additional details
Dates
- Accepted
-
2025-10-21