EFFICACY OF INTRAVESICAL PREDNISOLONE IN THE TREATMENT OF CHRONIC CYSTITIS COMPLICATED BY BLADDER ULCERATION

The study evaluated the effectiveness of intravesical prednisolone in 40 patients with chronic cystitis complicated by bladder ulceration. Patients were divided into three groups: standard therapy, prednisolone monotherapy, and combined treatment with antibiotics plus prednisolone. Prednisolone led to greater ulcer reduction, improved symptoms, and better inflammatory markers compared with standard therapy, while the combined regimen produced the strongest overall clinical response. Intravesical prednisolone was well tolerated and showed no systemic adverse effects. The findings support its use as an effective component in the management of ulcerative chronic cystitis.