Evaluation of fenugreek and flaxseed mucilage's as natural binders in pharmaceutical tablet formulation: a comparative study of physicochemical and tablet properties

Objective: To evaluate fenugreek (FGM) and flaxseed (FXM) mucilages as natural binders for pharmaceutical tablets. 
Methods: Mucilage was extracted, characterized (physicochemical, phytochemical, microbial analysis), and used to formulate tablets. Binding efficacy was assessed by testing tablet hardness, friability, and disintegration time against a gelatin standard. 
Results: Both mucilages were safe, carbohydrate-rich polymers. Tablets with FGM and FXM disintegrated faster (7:50 and 8:02 minutes, respectively) than gelatin tablets (10:36 minutes), while maintaining adequate mechanical strength.
Conclusion: FGM and FXM are effective, sustainable natural binders that enhance tablet disintegration, offering a eco-friendly alternative to synthetic binders.