Published November 30, 2025 | Version v1
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Formulation, Development and evaluation of Nitrofurantoin tablets drug delivery systems

  • 1. Assistant Professor, Department of Quality Assurance Technique, Samarth Institute of Pharmacy, Belhe, Pune, Maharashtra.
  • 2. Student, Samarth Institute of Pharmacy, Belhe, Pune, Maharashtra.

Description

Nitrofurantoin is a synthetic nitrofuran derivative widely used for the treatment and prevention of urinary tract infections (UTIs). It exhibits both bacteriostatic and bactericidal properties depending on its concentration. The formulation of Nitrofurantoin tablets aims to achieve optimum bioavailability, stability, and patient compliance. This review summarizes various approaches to the formulation and evaluation of Nitrofurantoin tablets, focusing on excipient selection, manufacturing methods, quality control parameters, and recent advances in sustained or controlled release systems. 

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