Published November 27, 2025 | Version v1

FERRITIN WITHOUT FIBROSIS: ASYMPTOMATIC HYPERFERRITINEMIA IN PRIMARY CARE (CASE REPORT)

  • 1. 1. Department of Family Medicine, Ministry of the National Guard-Health Affairs, King Abdulaziz Medical City, P.O. Box 9515, Jeddah, 21423, Saudi Arabia.

Description

Background:Elevated levels of serum ferritin are not commonly observed in individuals who are asymptomatic and have no underlying condition.In suchcases,hyperferritinemia is usually associated with liver inflammation, insulin resistance, or mild iron accumulation. It may also correlate with the severity of the underlying disease.

Case Presentation: A56-year-old male patient was seen in our primary health care center in the National Guard Health Affairs.His medical history included obesity, type 2 diabetes, brucellosis, and hypertension. He was found to have persistently high ferritin levels during routine medical check-ups, with readings consistently between 1300 and 1500. Imaging studies illustrated signs of hepatic steatosis compatible with fatty liver disease. A Fibroscan indicated no fibrosis, normal stiffness and mild fat accumulation. Liver iron study MRI showed moderate liver iron deposition.Further genetic tests ruled out hereditary hemochromatosis or other causes of secondary iron overload. Laboratory results for liver function were within normal limits.

 

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