Published November 16, 2025
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Infection Incidence in Penile Implant Revisions: A Forum-Based Analysis
Description
Background: Infection represents a serious complication following penile prosthesis implantation,
often necessitating device explantation and replacement. Understanding infection patterns in revision
cases is critical for patient counseling and surgical planning.
Methods: This study analyzed 1,255 penile implant procedures from 1,056 users documented on
FrankTalk.org using dual large language model (LLM) verification methodology. Users with multiple
procedures (n=146) were identified. Forum signatures and post histories underwent LLM-based
extraction with independent verification for explicit infection mentions.
Results: Among 146 revision users, 15 confirmed infections were identified (10.3% infection rate
among revision cases; 1.20% overall rate). Device distribution: Titan 6 cases (40%), CX 7 cases (47%),
LGX 1 case (7%), Others 1 case (7%). Time to infection: 10/15 (67%) occurred within 3 months,
suggesting early surgical-site contamination. Median time to revision (TTR) was 2 months (range: 0-27
months). Progressive infection risk analysis revealed escalating rates with successive procedures: ≥2
procedures 10.3%, ≥3 procedures 35.5%, ≥4 procedures 53.8%, closely aligning with published clinical
data.
Conclusions: Revision surgery carries a 10.3% infection risk, aligning with published estimates of
10-18% for revision procedures. Two-thirds of infections manifest within 3 months, emphasizing the
importance of early post-operative monitoring. Progressive risk analysis confirms escalating infection
rates with multiple revisions, though limited sample size for ≥4 procedures (n=13) precludes robust
statistical comparison at higher revision counts. No device-specific infection susceptibility was
observed.
often necessitating device explantation and replacement. Understanding infection patterns in revision
cases is critical for patient counseling and surgical planning.
Methods: This study analyzed 1,255 penile implant procedures from 1,056 users documented on
FrankTalk.org using dual large language model (LLM) verification methodology. Users with multiple
procedures (n=146) were identified. Forum signatures and post histories underwent LLM-based
extraction with independent verification for explicit infection mentions.
Results: Among 146 revision users, 15 confirmed infections were identified (10.3% infection rate
among revision cases; 1.20% overall rate). Device distribution: Titan 6 cases (40%), CX 7 cases (47%),
LGX 1 case (7%), Others 1 case (7%). Time to infection: 10/15 (67%) occurred within 3 months,
suggesting early surgical-site contamination. Median time to revision (TTR) was 2 months (range: 0-27
months). Progressive infection risk analysis revealed escalating rates with successive procedures: ≥2
procedures 10.3%, ≥3 procedures 35.5%, ≥4 procedures 53.8%, closely aligning with published clinical
data.
Conclusions: Revision surgery carries a 10.3% infection risk, aligning with published estimates of
10-18% for revision procedures. Two-thirds of infections manifest within 3 months, emphasizing the
importance of early post-operative monitoring. Progressive risk analysis confirms escalating infection
rates with multiple revisions, though limited sample size for ≥4 procedures (n=13) precludes robust
statistical comparison at higher revision counts. No device-specific infection susceptibility was
observed.
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